Star racecar Lightning McQueen and the incomparable tow truck Mater take their friendship on the road from Radiator Springs to exciting new places when they head overseas to compete in the first-ever World Grand Prix to determine the world's fastest car. But the road to the championship is filled with plenty of potholes, detours, and hilarious surprises when Mater gets caught up in an intriguing adventure of his own: international espionage!

While Scrat the Saber-toothed Squirrel is still trying to find his precious acorn, the misfit trio of Manny the Mammoth, Sid the Sloth and Diego the Sabre-tooth Tiger have settled down in an isolated valley with numerous other animals. However, the trio soon discover that the ice wall surrounding the valley is barely holding back a massive body of water behind it and the melting state threatens to break the wall and flood the valley. With their one...