Days after the encounter at the Swiss waterfall that claimed the lives of Sherlock Holmes and criminal mastermind Professor Moriarty, Pinkerton detective agent Frederick Chase and Scotland Yard Inspector Athelney Jones, a devoted student of Holmes's methods of investigation and deduction, must track down a sinister figure who is determined to stake his claim as Moriarty's successor.

Before James grew up to be a ruthless, remorseless villain, he was a curious boy from Boston, with a penchant for trouble and an acid tongue. Thrown into a boarding school against his wishes, James winds up rooming with a most unlikely companion: a lanky British know-it-all named Sherlock Holmes ("Lock" to his friends). An heirloom Bible, donated by the Moriarty family more than a hundred years ago, has gone missing, and it doesn't take long for the...

The threat of Moriarty is gone - but so is Sherlock Holmes. Even as they mourn the loss of their colleague, psychic Nan Killian, medium Sarah Lyon-White, and Elemental Masters John and Mary Watson must be vigilant, for members of Moriarty?s network are still at large. And their troubles are far from over- in a matter of weeks, two headless bodies of young brides wash up in major waterways. A couple who fears for their own recently-wedded daughter...

Sherlock Holmes has always been the smartest man in the room, until now. There is a new criminal mastermind at large, Professor James Moriarty, and not only is he Holmes's intellectual equal, but his capacity for evil, coupled with a complete lack of conscience, may give him an advantage over the renowned detective. Holmes's investigation into Moriarty's plot becomes more dangerous as it leads him and Watson out of London to France, Germany, and finally...

"London, 1943. Across the city, prominent figures in science and the military are bursting into flame and being incinerated. Convinced that the Germans have deployed a new terror weapon, a desperate government turns to the one man who can track down the source of this dreadful menace--Sherlock Holmes. The quest for a solution drives Holmes into an uneasy alliance with the country's most brilliant scientific genius, Professor James Moriarty. Only Sherlock...

Holmes and Watson come face to face with a formidable foe...Several hostages are caught in a deadly game... Sherlock and John race against time to solve a series of bizarre cases, free the victims, and uncover the culprit...This manga adapts 'The Great Game', the third episode of the smash-hit Hartswood Films TV show starring Benedict Cumberbatch as Holmes and Martin Freeman as Watson.