Jerry has to do one last errand for the mob before they let him find employment elsewhere -- he has to go to Mexico and recover a rare and very valuable pistol "The Mexican", which is said to be cursed. While his girlfriend, Samantha, objects to Jerry taking the assignment, he isn't in much of a position to argue. Once in Mexico, Jerry finds the pistol easily enough, but making his way back to the States proves to be an unexpected challenge. Meanwhile,...

Dr. Michael Hfuhruhurr invented zip-lock, screw-top brain surgery. The doctor pines for his late wife until a new woman sashays into his life. When they get married the truth emerges.

The next generation of Griswolds is at is again, and on the road for another ill-fated adventure. Following in his father's footsteps and hoping for some much-needed family bonding, a grown-up Rusty Griswold surprises his wife, and their two sons with a cross-country trip back to Wally World.